Biomedical applications of a new portable Raman imaging probe

This article reports the outline of a new portable Raman imaging probe and its applications. This probe may be the smallest and lightest Raman imaging probe in the world. It is equipped with an interchangeable long-working distance microscope objective lens. The irradiation area is about 45 and 90 mu m and the spatial resolution is 1 mu m. In the present study, the Raman imaging probe was used to obtain a Raman image of diamond particles and a Raman mapping of carotenoid in Euglena.