Author/Authors :
T. Andus، نويسنده , , M. Roth، نويسنده , , F. Kullmann، نويسنده , , I. Caesar، نويسنده , , V. Gross، نويسنده , , S. Feuerbach، نويسنده , , J. Sch?lmerich، نويسنده , , A. Geissler، نويسنده , , P. Held، نويسنده ,
Abstract :
Inflammatory bowel diseases are often associated with extra-intestinal manifestations, such as arthritis and iritis/uveitis. Using magnetic-resonance imaging we found hyperintense focal white-matter lesions in the brain in 20 of 48 (42%) patients with Crohnʹs disease, in 11 of 24 (46%) patients with ulcerative colitis, but in only 8 of 50 (16%) healthy age-matched controls (relative risk [95% Cl] vs controls 2·6 [1·3-5·3] and 2·9 [1·3-6·2], respectively). These findings may represent another extra-intestinal manifestation of inflammatory bowel disease.
