Author/Authors :
Mariëlle AE Nobbenhuis، نويسنده , , Theo JM Helmerhorst، نويسنده , , Adriaan JC van den Brule، نويسنده , , Lawrence Rozendaal، نويسنده , , Feja J Voorhorst، نويسنده , , P Dick Bezemer، نويسنده , , René H.M. Verheijen، نويسنده , , Chris J.L.M. Meijer، نويسنده ,
Abstract :
We studied the natural course of high-risk human papillomavirus (HPV) infection and cytological regression in women referred for colposcopy because of abnormal cervical smears. We found that high-risk HPV clearance preceded regression of cervical lesions by an average of 3 months. The cumulative 1-year rate of cytological regression was similar in women with mild and moderate dyskaryotic cervical smears. Thus, retesting of high-risk HPV after 6 months in women with mild to moderate dyskaryosis predicts cytological regression.