Title of article
Quantitative analysis of interleukin 6 (IL-6) in patients with IgA nephropathy after tonsillectomy
Author/Authors
Yuzo Baba، نويسنده , , Hirofumi Akagi، نويسنده , , Kunihiro Fukushima، نويسنده , , Michiya Kosaka، نويسنده , , Kenshi Hattori، نويسنده , , Kazunori Nishizaki، نويسنده , , Teruhiro Ogawa، نويسنده , , Yu Masuda، نويسنده , , Kenichi Shikata، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
177
To page
182
Abstract
The biological response to tonsillectomy was studied in 21 patients suffering from chronic tonsillitis with or without IgA nephropathy (IgAN). Serum and urinary interleukin-6 (IL-6) levels were measured before and after tonsillectomy. Serum IL-6 levels in case of IgAN peaked 3 h after tonsillectomy and more rapidly than control cases. No significant differences were observed between two cases through the time. Urinary IL-6 levels were significantly higher before and at 6 and 48 h after tonsillectomy in IgAN cases. Stimulation of tonsils caused serum IL-6 elevation and changes in urinary IL-6 levels in IgAN cases. Elevation of urinary IL-6 levels after tonsillectomy in patients with IgAN may reflect an increase in the production of IL-6 in the kidneys. Measurement of urinary IL-6 levels after tonsillectomy is useful to elucidate the efficacy of tonsillectomy in IgAN patients.
Keywords
IgA nephropathy , Interleukin-6 , tonsillectomy
Journal title
Auris Nasus Larynx
Serial Year
1999
Journal title
Auris Nasus Larynx
Record number
567258
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