Title of article
Assays for Functional Binding of Plasminogen to Viral Proteins
Author/Authors
Goto، Hideo نويسنده , , Kawaoka، Yoshihiro نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
-158
From page
159
To page
0
Abstract
Cleavage of the hemagglutinin (HA) molecule by proteases is a prerequisite for the infectivity of influenza A viruses. Plasminogen binds to the viral glycoprotein neuraminidase (NA), and NA-bound plasminogen is activated to plasmin, which cleaves the HA of influenza A/WSN/33 (WSN) (H1N1) virus. Here we present assays for detecting functional plasminogen binding to the influenza virus NA.
Keywords
membrane proteins , cell-cell communication , membrane biogenesis , protein phosphorylation , membrane channels
Journal title
METHODS : A COMPANION TO METHODS IN ENZYMOLOGY
Serial Year
2000
Journal title
METHODS : A COMPANION TO METHODS IN ENZYMOLOGY
Record number
57995
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