Title of article :
Rasagiline as an adjunct to levodopa in patients with Parkinsonʹs disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial
Author/Authors :
O Rascol، نويسنده , , D.J. Brooks، نويسنده , , E Melamed، نويسنده , , W Oertel، نويسنده , , W Poewe، نويسنده , , F Stocchi، نويسنده , , E Tolosa ، نويسنده ,
Abstract :
Background
Rasagiline mesylate is a novel drug for Parkinsonʹs disease with selective, irreversible monoamine oxidase B (MAO-B) inhibitor activity, and is effective as monotherapy in early disease. This study investigated rasagiline efficacy and safety in
