Author/Authors :
Timothy M. Cox، نويسنده , , Nicola Jack، نويسنده , , Simon Lofthouse، نويسنده , , John Watling، نويسنده , , Janice Haines، نويسنده , , Martin J Warren، نويسنده ,
Abstract :
In 1969 it was proposed that the episodic madness suffered by King George III (1738–1820) resulted from an acute hereditary porphyria, variegate porphyria, caused by deficiency of protoporphyrinogen oxidase. The diagnosis was based on the historical archi