Title of article :
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
Author/Authors :
Josef S. Smolen، نويسنده , , Andre Beaulieu، نويسنده , , Andrea Rubbert-Roth، نويسنده , , Cesar Ramos-Remus، نويسنده , , Josef Rovensky، نويسنده , , Emma Alecock، نويسنده , , Thasia Woodworth، نويسنده , , Rieke Alten، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Pages :
11
From page :
987
To page :
997
Abstract :
Background Interleukin 6 is involved in the pathogenesis of rheumatoid arthritis via its broad effects on immune and inflammatory responses. Our aim was to assess the therapeutic effects of blocking interleukin 6 by inhibition of the interleukin-6 recepto
Journal title :
The Lancet
Serial Year :
2008
Journal title :
The Lancet
Record number :
592657
Link To Document :
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