Title of article :
Efficacy of ISA247 in plaque psoriasis: a randomised, multicentre, double-blind, placebo-controlled phase III study
Author/Authors :
K Papp، نويسنده , , R Bissonnette، نويسنده , , L Rosoph، نويسنده , , N Wasel، نويسنده , , CW Lynde، نويسنده , , G Searles، نويسنده , , NH Shear، نويسنده , , RB Huizinga، نويسنده , , WP Maksymowych، نويسنده ,
Abstract :
Background
The use of systemic calcineurin inhibitors for the treatment of patients with psoriasis is limited by toxicity, particularly nephrotoxicity. ISA247, a novel inhibitor, was effective and well tolerated in a phase II study of patients with plaque
