Reconstruction of diaphragm using autologous fascia lata: an experimental study in dogs

Background. We investigated whether fascia lata is an appropriate material for reconstruction of the diaphragm. Methods. A diaphragmatic defect (2 cm by 5 cm) was reconstructed with a patch of autologous fascia lata in the experimental group (n = 12) and with expanded polytetrafluoroethylene in the control group (n = 12). Maximal tensile strength at the sutured region was measured serially. Results. The maximal tensile strength at the sutured region reconstructed with the fascia lata was 1.14 ± 0.50 kgf 15 days and 2.04 ± 0.94 kgf 30 days after operation. The values were higher than those of expanded polytetrafluoroethylene (p< 0.0001). These values of fascia lata were close to the original maximal tensile strength of the muscular region of the diaphragm (1.52 to 1.66 kgf). Conclusions. Reconstruction of diaphragm using autologous fascia lata is safe, easy, and inexpensive, and provides smooth wound healing. The only disadvantage is the necessity of a femoral incision for harvest; nevertheless, it may be worthwhile to use fascia lata in clinical trials to further assess its suitability as a reconstruction material. Background. We investigated whether fascia lata is an appropriate material for reconstruction of the diaphragm. Methods. A diaphragmatic defect (2 cm by 5 cm) was reconstructed with a patch of autologous fascia lata in the experimental group (n = 12) and with expanded polytetrafluoroethylene in the control group (n = 12). Maximal tensile strength at the sutured region was measured serially. Results. The maximal tensile strength at the sutured region reconstructed with the fascia lata was 1.14 ± 0.50 kgf 15 days and 2.04 ± 0.94 kgf 30 days after operation. The values were higher than those of expanded polytetrafluoroethylene (p< 0.0001). These values of fascia lata were close to the original maximal tensile strength of the muscular region of the diaphragm (1.52 to 1.66 kgf). Conclusions. Reconstruction of diaphragm using autologous fascia lata is safe, easy, and inexpensive, and provides smooth wound healing. The only disadvantage is the necessity of a femoral incision for harvest; nevertheless, it may be worthwhile to use fascia lata in clinical trials to further assess its suitability as a reconstruction material.