Author/Authors :
Michael K. Pasque، نويسنده , , Tina Hanselman، نويسنده , , Kim Shelton، نويسنده , , Beth A. Kehoe-Huck، نويسنده , , Robyn Hedges، نويسنده , , Stephen D. Cassivi، نويسنده , , Gregory A. Ewald، نويسنده , , Joseph G. Rogers، نويسنده ,
Abstract :
Implantable left ventricular assist device (LVAD) drive-line exit site infection, an expected consequence of currently available device use, continues to be a significant limiting factor in long-term support. We theorize that the mechanism behind the establishment of the most chronic exit site infections involves a shearing torsion injury that disrupts the tissue adherence interface with the drive-line. The resulting neo-epithelialized drainage tract prevents permanent clearance of the infection with antibiotics alone. The proposed treatment strategy of established infections involves aggressive surgical excision of the involved exit site.
