Author/Authors :
Lu?s Henrique W. Gowdak، نويسنده , , Isolmar T. Schettert، نويسنده , , Carlos Eduardo Rochitte، نويسنده , , Luiz Augusto F. Lisboa، نويسنده , , Lu?s Alberto O. Dallan، نويسنده , , Luiz Antônio M. César، نويسنده , , Jose Eduardo Krieger، نويسنده , , José Antônio F. Ramires، نويسنده , , Sergio A. de Oliveira، نويسنده ,
Abstract :
We describe the use of autologous bone marrow cells combined with transmyocardial laser revascularization in a 74-year-old man with refractory angina. Baseline cardiac magnetic resonance imaging revealed a markedly depressed left ventricle systolic function and an extensive area of myocardial ischemia. During surgery, 11 laser shots using a CO2 Heart Laser System (PLC Medical Systems, Milford, MA) were fired and a 5-mL cell suspension containing 21.5 × 106 bone marrow cells/mL was delivered by multiple injections into the myocardium. At 6 months after the procedure, another cardiac magnetic resonance imaging showed an almost complete resolution of the perfusion defect and an improvement in left ventricular contractility.
