Human colonic microvascular endothelial cells is a model of inflammatory bowel disease

Background The pathophysiology of inflammatory bowel disease remains elusive primarily because of the limitations of the models available for study in the basic science laboratories. We propose a new model for the study of inflammatory bowel disease. Data Sources Research and review articles published in the English literature. Conclusions The human colonic microvascular endothelial cell in culture is a legitimate model for the study of the human colon in the normal and diseased states.