Title of article :
Colon carcinoma in patients undergoing liver transplantation
Author/Authors :
Renata Fabia، نويسنده , , Marlon F. Levy MD، نويسنده , , Giuliano Testa MD، نويسنده , , Samuel Obiekwe، نويسنده , , Robert M. Goldstein MD، نويسنده , , Bo S. Husberg MD PhD، نويسنده , , Thomas A. Gonwa MD، نويسنده , , Goran B. Klintmalm MD PhD، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
5
From page :
265
To page :
269
Abstract :
Background: Organ recipients are at risk for certain neoplasms. Ulcerative colitis (UC) is itself a strong risk factor for the development of colon carcinoma (CCa). Transplant patients with UC might be at higher risk for CCa. We analyzed these patients to compare the incidence and pattern of CCa development in these and non-UC patients following liver transplantation (OLTX). Patients and methods: Retrospective study of 1,085 OLTX patients. Results: In 1,022 patients without UC, 1 patient (<0.1%) developed adenocarcinoma in a colonic polyp 46 months after OLTX. Sixty-three of 108 (60%) patients undergoing OLTX simultaneously had UC. Five OLTX patients (8%) with UC developed colon adenocarcinoma 22 to 66 (mean 48) months after OLTX. Two have died. Conclusions: Coexistent UC in patients requiring OLTX constitutes a potentially high risk for the development of colonic cancer, a late-appearing event. These patients require close observation and frequent colonoscopic/histologic screening of the colon.
Journal title :
The American Journal of Surgery
Serial Year :
1998
Journal title :
The American Journal of Surgery
Record number :
620389
Link To Document :
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