Meaurement of microcirculation in optic nerve head by laer peckle flowgraphy in normal volunteer

PURPOE: To report blood flow in the optic nerve head between the right and left eye or the uperior and inferior neuroretinal rim in normal volunteer uing laer peckle flowgraphy. METHOD: Thi propective tudy included 120 eye of 60 normal volunteer (mean age, 50.0 ± 16.9 year; range, 21 to 77 year). The quare blur rate wa meaured by laer peckle flowgraphy (Kyuhu Intitute of Technology, Iizuka, Japan). The equence of eye meaurement wa randomized. In each eye, meaurement were taken at the neuroretinal rim away from viible veel. Linear regreion analyi, paired two-tailed t tet, and two-way analyi of variance were ued for tatitical analyi. P value le than .05 were accepted a tatitically ignificant. REULT: There wa a ignificant correlation in quare blur rate between the right and left eye (r = 0.587, P < .001). quare blur rate in the uperior temporal neuroretinal rim ignificantly correlated with that in the inferior temporal neuroretinal rim in each of the right (r = 0.546, P < .001) and left (r = 0.465, P < .001) eye. quare blur rate in the right eye wa higher than that in the left eye (P = .049). quare blur rate in the uperior neuroretinal rim wa higher than that in the inferior neuroretinal rim in both the right (P = .035) and left (P = .005) eye. CONCLUION: There were tatitically ignificant difference of optic nerve head blood flow in normal volunteer uing laer peckle flowgraphy between the right and left eye and between the uperior and inferior temporal neuroretinal rim. Thee normal data can be ued for undertanding phyiological ocular hemodynamic.