Retinal ichemia and angle neovacularization in proliferative diabetic retinopathy

PURPOE: To analyze the relationhip between the extent of retinal ichemia in proliferative diabetic retinopathy and angle neovacularization. METHOD: Panoramic fundu fluorecein angiography and 360-degree fluorecein gonioangiography to detect the angle neovacularization were performed on 70 eye of 46 patient with proliferative diabetic retinopathy. tatitical ignificance wa evaluated by chi-quared tet. tatitical ignificance wa evaluated if the value (T) wa greater than the level of ignificance, χ0.052(2) = 5.99. REULT: Retinal ichemia in fluorecein angiography wa evaluated in four area: capillary occluion in (1) temporal raphe; (2) radial peripapillary capillarie; (3) the midperiphery (grade I, le than 25% of the area; grade II, 25% to 50%; grade III, 50% to 75%; grade IV, more than 75%); and (4) optic dik with neovacularization. The angle neovacularization wa divided into two type: type I (14 eye) and type II (12 eye). Capillary occluion in the temporal raphe and radial peripapillary capillarie, and papillary leakage ignificantly increaed the rik of angle neovacularization (T = 8.28, 10.04, 6.44 repectively). Grade III and IV capillary occluion in the midperiphery had a ignificant rik of angle neovacularization when compared with grade I (between grade III: T = 9.03, grade IV: T = 19.36) and II (between grade III: T = 6.31, grade IV: T = 16.09). CONCLUION: Rik factor for angle neovacularization were retinal nonperfuion in the midperiphery wider than grade III, capillary occluion in the radial peripapillary capillarie and temporal raphe, and optic dik. Fluorecein gonio angiography wa found to be a powerful tool for the early detection of angle neovacularization, epecially in dark iride.