Recurring tranitory blindne caued by primary marginal pigment epithelial iri cyt

PURPOE: To report four cae of primary pupillary pigment epithelial iri cyt, all member of one family, in which two of the patient had recurring tranitory viual impairment. METHOD: Obervational cae erie. Hitory wa taken, the patient were examined with lit-lamp and ultraound biomicrocopy, and urgically removed cyt tiue wa examined with tranmiion electron microcopy. REULT: Pupillary pigment epithelial cyt of the iri generally how an autoomal dominant heredity pattern, with occaional lack of penetrance. In two of our cae, the ize and location of the cyt caued viual ymptom, neceitating urgical removal. The cyt wall conit entirely of pigment epithelial cell. CONCLUION: The origin of pupillary pigment epithelial cyt i unclear, and a hereditary background i very likely. Their clinical ignificance i in their imilarity to pigmented tumor of the iri. They may alo be indicative of coexiting ytemic dieae. In ymptomatic cae, treatment i indicated