Vitreou hemorrhage in patient with high-rik retinopathy of prematurity

Purpoe To invetigate outcome in premature infant with high-rik retinopathy of prematurity and econdary vitreou hemorrhage. Deign Retropective chart review. Method Patient were elected from a databae of infant undergoing retinopathy of prematurity creening from eptember 1997 to November 1999. Infant with high-rik retinopathy of prematurity (zone I or poterior zone II threhold dieae) with and without vitreou hemorrhage were compared. Main outcome meaure Final tage of retinopathy of prematurity and hort-term tructural outcome were aeed. Viual acuity and refraction were meaured when poible. Reult Twenty-two eye of 11 patient (group 1) had high-rik (poterior zone II or zone I threhold) retinopathy of prematurity without vitreou hemorrhage. Group 1 patient had a 91% favorable hort-term tructural outcome. Eight eye of five infant developed vitreou hemorrhage with high-rik retinopathy of prematurity (group 2). Group 2 patient had only a 12.5% favorable hort-term tructural outcome. even of eight (87.5%) progreed to tage IVa or IVb retinopathy of prematurity. ix eye underwent vitreoretinal urgery after a median duration of hemorrhage of 36 ± 29 day (4–70 day). Three eye developed tage V detachment and three progreed to phthiical degeneration. Final viual acuity wa no light perception in three eye. Concluion Vitreou hemorrhage, in aociation with advanced retinopathy of prematurity, i a poor prognotic ign.