Ophthalmic imaging by pectral optical coherence tomography

Purpoe To demontrate two novel ophthalmic imaging technique baed on fat pectral Optical Coherence Tomography (OCT). Deign Propective obervation cae report. Method etting Reearch laboratory. tudy population A normal human ubject. Main outcome meaure Correlation of an optical coherence retinal tomogram with known retinal anatomy, reduction of eye expoure to the probing light beam during Optical Coherence Tomography (OCT) examination. Reult High reolution (3- × 20-μm) cro-ectional 2-dimenional image of the human retina in vivo have been obtained with only 0.1-econd total illumination time (for 1024 A-can), and approximately 200- μW eye expoure. Detail of the optic dik in vivo have been viualized at a rate of eight frame per econd, which i ufficient to provide real time analyi. The 3-dimenional image of the optic nerve correpond to the image obtained from a fundu camera. Concluion Becaue of it hort acquiition time and high enitivity, OCT ue a 100 time lower expoure/A-can to obtain image of comparable quality to thoe obtained by the commercial intrument baed on traditional time-domain OCT. pectral Optical Conherence Tomography therefore provide a much wider afety margin than the traditional method and allow relaxation of the current afety precaution forbidding more than 10 minute/day canning of the ame location of a retina. A a reult of the high peed offered by the new technique, the 3-dmenional tomogram, which allow a urgeon acce to a comprehenive and detailed view of relevant pathologie, are obtained in a much horter, clinically more reaonable time.