Inter-eye difference in diabetic macular edema after unilateral intravitreal injection of triamcinolone acetonide

Purpoe To report on viual outcome of patient receiving intravitreal triamcinolone acetonide for treatment of diffue diabetic macular edema. Deign Propective, comparative clinical interventional tudy. Method etting: Intitutional. patient population: The tudy included 25 conecutive patient (50 eye) with bilateral diabetic macular edema. intervention procedure: Unilateral intravitreal injection of about 20 mg triamcinolone acetonide into the eye (tudy group) more everely affected by diabetic maculopathy. The contralateral eye erved a control group. Mean follow-up wa 7.1 ± 4.1 month. main outcome meaure: Viual acuity, intraocular preure. Reult In the tudy group, viual acuity increaed ignificantly (P ≤ .001) by 3.0 ± 2.6 nellen line to a peak at two to ix month after the injection, and decreaed ignificantly (P = .001) toward the end of follow up. At the end of follow-up, viual acuity wa higher, not ignificantly (P = .18) higher, than at baeline. An increae in viual acuity wa found in 23 eye (92%). In the control group, difference between viual acuity at baeline and at any of the re-examination during follow-up were not ignificant (P > .10). In an intra-individual inter-eye comparion, gain in viual acuity wa ignificantly (P < .05) higher in the injected eye, for the meaurement obtained up to four month after injection. Concluion Intravitreal triamcinolone acetonide may temporarily increae viual acuity in eye with diabetic macular edema.