Long-term efficacy of adding a harp poterior optic edge to a three-piece ilicone intraocular len on capule opacification: Five-year reult of a randomized tudy

Purpoe To compare the intenity of capule opacification with the harp and the round optic edge variant of an open-loop hydrophobic ilicone intraocular len (IOL). Deign Randomized, controlled, double-blind clinical trial with intraindividual comparion. Method Fifty-one patient with bilateral age-related cataract were included (102 eye). Each patient had had cataract urgery in both eye and received a Microil IOL with a harp optic edge deign (model ) in one eye and a Microil IOL with a round optic edge deign (model R) in the fellow eye. Both IOL had an identical haptic deign (nonangulated polymethylmethacrylate) and ilicone optic material. The patient were examined at the lit lamp, bet-corrected viual acuity wa aeed, and tandardized high-reolution digital retroillumination image of the poterior capule were taken 5 year after urgery. The intenity of regeneratory poterior capule opacification (rPCO), fibrotic PCO (fPCO), and anterior capule opacification (ACO) wa aeed ubjectively at the lit lamp, and of rPCO, objectively uing automated image analyi oftware (AQUA). The need for an Nd:YAG laer capulotomy (Nd:YAG-LCT) wa noted. Reult The mean AQUA PCO core wa 1.2 for the model and 2.4 for the model R len (P = .001). The model len alo led to le peripheral fPCO (P = .003). Concerning ACO, there wa no ignificant difference between both IOL group (P = .72). Wherea no capulotomy wa required with the model , four cae (16%) had been performed in the model R group. Concluion Five year potoperatively, the harp-edged ilicone IOL howed le rPCO and fPCO than the round-edged IOL. However, regarding ACO, there wa no ignificant difference between both IOL tyle.