Corneal enitivity change following the intillation of latanoprot, bimatoprot, and travoprot eyedrop

Purpoe To examine central corneal mechanical enitivity (CCM) after the intillation of latanoprot, travoprot, and bimatoprot. Deign Nonrandomized interventional tudy. Method Latanoprot wa ued in 24 patient (43 eye), travoprot in 21 patient (42 eye), and bimatoprot in 15 patient (28 eye). CCM wa examined with the Cochet-Bonnet etheiometer before the intillation of protaglandin analog and then 5 and 30 minute later. Examination of chirmer and breakup time (BUT) tet were alo performed. Thirty healthy ubject were examined a a control group. Reult CCM wa ignificantly reduced at the 5-minute interval for latanoprot (P = .03), travoprot (P = .04), and bimatoprot (P = .04). Difference between the three analog were tatitically not ignificant. CCM change ignificantly correlated with chirmer and BUT tet core. Concluion The correlation between CCM reduction and BUT and chirmer tet core implie that the ue of artificial tear may be conidered if protaglandin analog are adminitered.