Chlamydia Conjunctiviti and Central Retinal Vein Occluion

Purpoe To report a cae of coexitent Chlamydia conjunctiviti and central retinal vein occluion (CRVO) in which both problem improved ignificantly after oral doxycyline. Deign Interventional cae report. Method A healthy 39-year-old man preented with follicular and papillary conjunctiviti, unreponive to topical antibiotic therapy, and a CRVO. The patient had erum IgG titer of 1:256 to both Chlamydia pneumonia and Chlamydia trachomatou. Reult Treatment with oral doxycyline (100 mg orally twice daily for 2 week) reulted in complete reolution of the conjunctiviti and rapid improvement of the CRVO. Concluion Becaue of it ability to caue chronic vacular endothelial infection and localized inflammation, Chlamydia ha been implicated in the development of arterial vacular dieae. The poitive Chlamydia erology, conjunctiviti, CRVO, and excellent repone to doxycycline in thi patient ugget that Chlamydia may have contributed to hi vacular occluion. Further tudie invetigating a poible aociation between Chlamydia and CRVO may be indicated.