Long-Term Follow-up of Fixation Pattern in Eye With Central cotoma From Geographic Atrophy That I Aociated With Age-Related Macular Degeneration

Purpoe To tudy whether fixation pattern changed over time in patient with central cotoma from geographic atrophy from age-related macular degeneration. Deign Propective cohort tudy. Method etting: Intitutional. patient or tudy population: Propective natural hitory tudy of geographic atrophy included 34 eye of 25 patient with baeline acuity between 20/80 and 20/200 and with ubequent follow-up. obervation procedure: Baeline and annual follow-up viit included bet-corrected viual acuity, canning laer ophthalmocope macular perimetry, reading rate, and clinical evaluation. main outcome meaure: Location of eccentric preferred retinal locu for fixation (PRL). Reult At baeline, 77% of tudy eye had a PRL. At the final viit (median follow-up, 5.3 year), 91% of tudy eye had a PRL, with 81% of the eye retaining the baeline PRL location. Fixation with the cotoma to the right and fixation with the cotoma uperior were the firt and econd mot common fixation pattern, repectively. Reading rate of <50 word/min were preent in 54% of eye. Eye fixating with the cotoma to the left tended to have lower reading rate than eye fixating with right or uperior pattern. Concluion Fixation with right pattern remained the mot common fixation pattern, both in patient with a PRL at baeline and in patient who had a PRL during follow-up. Eye with a PRL at baeline generally retained thi pattern. The reading rate data ugget an advantage of fixation with right or uperior pattern, rather than left. Reading rate declined further during follow-up in mot patient.