Higher-order Aberration in Children

Purpoe To quantify and characterize higher order aberration in children and to invetigate the influence of refractive error and cycloplegia. Deign Obervational cro-ectional tudy. Method etting: Clinical practice. patient: One hundred ixty-two eye of 82 children were examined. The mean age of the children wa 6.7 year (range, 4 to 14 year), and the mean manifet refractive pherical equivalent wa 2.39 ± 3.35 diopter (range, −8.98 to +8.45 diopter). Aberrometry wa performed with a wavefront analyzer (after cycloplegia and mydriai with cyclopentolate 1%). Aberrometry wa alo conducted on a ubgroup of 52 eye of 27 children, both before and 30 minute after the intillation of cyclopentolate 1% to invetigate the effect of paralyi of accommodation. Reult Mean root mean quare value of total-, third-, fourth-, and fifth-order aberration were 0.37 ± 0.13 μm, 0.23 ± 0.12 μm, 0.16 ± 0.11 μm, and 0.08 ± 0.12 μm, repectively. Mean root mean quare value of total coma (Z3−1, Z31, Z5−1, Z51) and total trefoil (Z3−3, Z33, Z5−3, Z53) were 0.27 ± 0.31 μm and 0.21 ± 0.29 μm, repectively. Myope had tatitically ignificant greater level of total (P = .005) and fourth order (P = .002) aberration and Zernicke term (Z3−3, Z3−1, Z33, Z4−4, and Z42) compared with hyperope. Cycloplegia had minimal influence on higher-order aberration. Concluion ignificant level of higher-order aberration were found in thee children. They were influenced by refractive error, becaue myope had ignificantly greater level compared with hyperope. Paralyi of accommodation with cyclopentolate appeared to have little effect on higher-order aberration.