Long-term Follow-up of Intermediate Uveiti in Children Original Reearch Article

Purpoe To analyze the clinical manifetation, remiion, and viual prognoi of intermediate uveiti in children, and to identify the rik factor for poor viual outcome. Deign Retropective cohort tudy. Method Intitutional tudy of 32 conecutive patient examined at a tertiary referral center with intermediate uveiti and the onet of ocular dieae before the age of 16 year. Numerou variable were aeed, including age and gender ditribution, laboratory data, the preence of ytemic dieae, onet and coure of ocular inflammation, clinical feature and complication, therapeutic trategie and their outcome, remiion and final viual acuity, and characteritic aociated with poor viual outcome. Reult Bilateral involvement wa oberved in 94% of the patient. Remiion wa oberved in even out of 15 patient (47%) with completed follow-up of five year. For our 32 ubject, we found a mean time to remiion of 6.4 year (E 0.7, CI 5.1 to 7.7). Viual outcome wa favorable a only three patient developed unilateral acuity of le than 0.1 after five-year follow-up, and no additional blind eye manifeted. No aociated ytemic dieae were etablihed. Optic dik edema wa the mot frequent complication oberved (71%). Cytoid macular edema (CME) wa oberved in 44% of the patient and wa the mot common caue of viual lo. Concluion Intermediate uveiti of childhood might exhibit a elf-limiting coure after everal year. Viual lo wa limited depite the high rate of evere ocular complication.