Retinal Nerve Fiber Layer Thickne in Amblyopic Eye Original Reearch Article

Purpoe To compare the peripapillary retinal nerve fiber layer (RNFL) thickne of ound and amblyopic eye. Deign Propective obervational cae erie. Method etting: Intitutional. tudy population: Patient with unilateral trabimic, aniometropic, or combined amblyopia. obervation: Fat RNFL analyi with ocular coherence tomography (OCT) of ound and amblyopic eye. meaure: Mean RNFL thickne. Reult For the 17 patient (mean age 10.7 year) in whom both eye were imaged, the mean thickne of the ound eye wa 109.2 μm (median 112.7) and of the amblyopic eye wa 104.2 μm (median 105.0), and the average difference (ound eye le amblyopic eye) wa 5.0 μm (median 3.0) (95% confidence interval −2.3, 12.2, P = .17). The ound eye wa 10 μm or more thicker than the amblyopic eye in four patient; the amblyopic eye wa 10 μm or more thicker than the ound eye in one patient; and the difference wa within 10 μm in 12 patient. Tet-retet data were obtained for 23 pair of ound eye and 21 pair of amblyopic eye, with 75% of the tet-retet pair within 7%. Concluion We found a mall, but not clinically ignificant, difference in nerve fiber layer (NFL) thickne between amblyopic and ound eye. Reliability wa excellent, with mot eye teting within 7% of the firt tet.