Title of article :
Management of Periocular Baal and quamou Cell Carcinoma: A erie of 485 Cae Original Reearch Article
Author/Authors :
Arie Y. Nemet، نويسنده , , Yael Deckel، نويسنده , , Peter A. Martin، نويسنده , , Georgina Kourt، نويسنده , , Michael Chilov، نويسنده , , Viduhi harma، نويسنده , , Ro Benger، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
Purpoe
To analyze the outcome of management of patient with baal cell carcinoma (BCC) and quamou cell carcinoma (CC) in a tertiary referral eye center in ydney, Autralia.
Deign
Retropective cae erie.
Method
Review of medical record of 485 conecutive cae (469 patient) with confirmed eyelid cancer. intervention procedure: urgical exciion with 3- to 5-mm clinically clear margin and hitologic confirmation of the urgical margin. Frozen ection hitology or Moh’ micrographic urgery (MM) wa ued for incompletely excied cae, and thoe located in the medial canthu or cloe to the lacrimal drainage ytem. tandard recontruction technique were employed. main outcome meaure: urvival period free of tumor, incomplete exciion, recurrence, type of cloure, and complication.
Reult
Exciion wa initially incomplete in 25.4% of all tumor. Morpheaform type of BCC (χ2 P < .001), and medial canthu location BCC (χ2 P < .05) were aociated with a higher incomplete reection rate. A 35.9% incomplete exciion rate wa aociated with a ignificantly higher recurrence rate compared with complete exciion (8.4% and 4.6%, repectively, χ2 P < .05). Twenty-even patient (5.6%) had a recurrent tumor. After incomplete exciion, there wa no recurrence with MM, but 4.7% recurrence rate when frozen ection technique wa ued (P < .05). Local potoperative complication occurred in 41 patient (8.5%).
Concluion
In the etting of a tertiary referral center, incomplete primary reection of an eyelid kin cancer i the main rik factor for recurrence. Incomplete reection i ignificantly aociated with medial canthu location and morpheaform type of BCC and with moderately differentiated CC. MM i the afer technique after incomplete tumor exciion.
Journal title :
American Journal of Ophthalmology
Journal title :
American Journal of Ophthalmology