Intracranial Vacular Anomalie in Patient With Morning Glory Dik Anomaly Original Reearch Article

Purpoe An aociation between morning glory dik anomaly (MGDA) and intracranial vacular anomalie including Moyamoya dieae ha been recognized. We evaluated a erie of patient with MGDA to acertain the frequency of cerebrovacular anomalie. Deign Retropective obervational cae erie. Method We reviewed the neurologic hitorie and neuroimaging tudie of twenty patient with MGDA at two intitution between 1982 and 2004. Magnetic reonance imaging (MRI) and magnetic reonance angiography (MRA) of the brain wa performed on all patient who had not undergone neuroimaging. MRI/MRA tudie done for 40 pediatric patient without MGDA were alo evaluated for cerebrovacular anomalie. The prevalence of anomalie in the two group wa compared by Fiher exact tet. Reult Nine of 20 patient (45%) with MGDA had cerebrovacular anomalie. Anomalie ranged from agenei of the A1 egment of the anterior cerebral artery to bilateral tenoi of the internal carotid arterie with moyamoya dieae. Three patient underwent revacularization procedure. Ten of 40 patient (25%) in the control group had any intracranial vacular anomaly, wherea only two of 40 (5%) had an abnormality of the anterior circulation, the mot common finding in the MGDA group. Concluion We recommend that all patient with MGDA undergo MRI/MRA or computerized tomographic angiography to detect vacular and tructural brain anomalie. It may be unclear whether cerebrovacular anomalie repreent iolated congenital anomalie or finding of progreive occluive cerebrovacular dieae. Follow-up imaging hould be conidered in patient with cerebrovacular anomalie and i clearly indicated if neurologic ign or ymptom are preent.