Treatment Outcome in the Tube Veru Trabeculectomy tudy After One Year of Follow-up Original Reearch Article

Purpoe To report one-year reult of the Tube Veru Trabeculectomy (TVT) tudy. Deign Multicenter randomized clinical trial. Method etting: 17 Clinical Center. tudy population: Patient 18 to 85 year of age who had previou trabeculectomy and/or cataract extraction with intraocular len implantation and uncontrolled glaucoma with intraocular preure (IOP) ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy. intervention: 350 mm2 Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). main outcome meaure: IOP, viual acuity, and reoperation for glaucoma. Reult A total of 212 eye of 212 patient were enrolled, including 107 in the tube group and 105 in the trabeculectomy group. At one year, IOP (mean ± D) wa 12.4 ± 3.9 mm Hg in the tube group and 12.7 ± 5.8 mm Hg in the trabeculectomy group (P = .73). The number of glaucoma medication (mean ± D) wa 1.3 ± 1.3 in the tube group and 0.5 ± 0.9 in the trabeculectomy group (P < .001). The cumulative probability of failure during the firt year of follow-up wa 3.9% in the tube group and 13.5% in the trabeculectomy group (P = .017). Concluion Nonvalved tube hunt urgery wa more likely to maintain IOP control and avoid peritent hypotony or reoperation for glaucoma than trabeculectomy with MMC during the firt year of follow-up in the TVT tudy. Both urgical procedure produced imilar IOP reduction at one year, but there wa le need for upplemental medical therapy following trabeculectomy with MMC.