Title of article :
Conjunctival Pottranplantation Lymphoproliferative Diorder
Author/Authors :
R. Chritopher Walton، نويسنده , , Mihaela M. Onciu، نويسنده , , Farhan A. Irhad، نويسنده , , Terry D. Wilon، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Purpoe
To decribe a patient with conjunctival pottranplantation lymphoproliferative diorder (PTLD).
Deign
Interventional cae report.
Method
A 8-year-old boy, three month tatu pot bone marrow tranplantation with bilateral enlarged gelatinou bulbar conjunctiva wa examined. Biopy of the bulbar conjunctiva wa performed.
Reult
Conjunctival biopy revealed a polymorphou infiltrate of lymphoid cell with large atypical immunoblatic lymphoma cell, plamacytoid lymphocyte, and plama cell. B-cell marker CD20 and CD79a were poitive. Plama cell exhibited retriction for kappa immunoglobulin light chain and were poitive for CD79a. Mot cell were poitive for Eptein-Barr viru (EBV) encoded ribonucleic acid. EBV-related polymorphic PTLD wa diagnoed and treated with dicontinuation of cycloporine, reduction in prednione doage and adminitration of EBV-pecific cytotoxic T lymphocyte. The conjunctival leion reolved during the next five week.
Concluion
Pottranplantation lymphoproliferative diorder rarely involve the ocular tructure with mot cae preenting a a maquerade yndrome. Thi cae illutrate that PTLD can involve the conjunctiva and further expand the clinical pectrum of ocular PTLD.
Journal title :
American Journal of Ophthalmology
Journal title :
American Journal of Ophthalmology