The Influence of Previou Orbital Irradiation on the Outcome of Rehabilitative Decompreion urgery in Grave Orbitopathy Original Reearch Article

Purpoe To invetigate whether orbital irradiation influence the outcome of decompreion urgery in Grave orbitopathy. Deign Retropective, comparative cae erie. Method The medical record of all the patient with Grave orbitopathy treated with a three-wall orbital decompreion through a coronal approach at our intitution between January 1, 1990 and December 31, 2000 were reviewed. Only patient who underwent bilateral urgery for aethetic rehabilitation, without preoperative diplopia, and who, in the active phae of the dieae, had received orbital radiotherapy alone (20 Gray (Gy) in 10 daily fraction of two Gy over a period of two week; group R), ytemic glucocorticoid alone (daily adminitration for more than three month independently from the doage; group G), or both radiotherapy and glucocorticoid (group RG) were elected. Group were compared for demographic, moking habit, preoperative characteritic, and urgical outcome (mean reduction of exophthalmo, reduction of lid retraction, peritence of periorbital welling requiring cometic eyelid urgery, onet of diplopia within 20 degree of the central poition of gaze, and variation in the peripheral field of diplopia). Reult ixty-one of 376 patient were elected for thi tudy. There were no difference between group R (n = 29), group G (n = 15), and group RG (n = 17) with repect to demographic or predecompreion characteritic, wherea the number of moker wa ignificantly greater in group RG (P= .019). We could not find difference in urgical outcome by comparing the three group. Concluion The total radiation doe, fraction ize, and irradiated volume commonly ued to treat active Grave orbitopathy do not adverely interfere with the outcome of rehabilitative decompreion urgery.