Role of Optic Nerve Imaging in Glaucoma Clinical Practice and Clinical Trial Original Reearch Article

Purpoe To provide an update on the role of optic nerve and peripapillary retinal nerve fiber layer imaging in glaucoma clinical practice and clinical trial. Deign Perpective. Method Review of recent literature and author’ clinical and laboratory tudie. Reult Imaging technologie uch a confocal canning laer ophthalmocopy, canning laer polarimetry, and optical coherence tomography provide objective and quantitative meaurement that are highly reproducible and how very good agreement with clinical etimate of optic nerve head tructure and viual function. tructural aement provided by imaging complement optic dik photography in clinical care and have the potential to identify relevant tructural efficacy endpoint in glaucoma randomized clinical trial. A with other technologie, imaging may produce fale identification of glaucoma and it progreion; thu, clinician hould not make management deciion baed olely on the reult of one ingle tet or technology. Concluion Although optic dik tereophotography repreent the tandard for documentation of glaucomatou tructural damage in practice and reearch trial, advance in computerized imaging technology provide ueful meaure that ait the clinician in glaucoma diagnoi and monitoring and offer coniderable opportunity for ue a efficacy endpoint in clinical trial.