Fundu Autofluorecence in Multifocal Choroiditi and Panuveiti Original Reearch Article

Purpoe To invetigate the autofluorecence finding aociated with multifocal choroiditi and panuveit (MCP), a condition that ha marked potential to affect the retinal pigment epithelium (RPE). Deign Obervational cae erie. Method Thi i a retropective review of conecutive patient with MCP examined in a retinal referral practice. Each patient wa given a comprehenive examination including fundu photograph, angiographic tudie, and autofluorecence photography with an excitation filter with the bandpa wavelength of 535 to 585 nm and a barrier filter with a bandpa of 615 to 715 nm. Integrative analyi wa performed of the ocular imaging to acertain abnormalitie caued by the dieae. Reult Thirty-ix eye of 18 conecutive patient were evaluated. The mean duration of ymptom wa 86.2 month and the mean viual acuity wa 20/50. Of the 36 eye, 23 had choroidal neovacularization (CNV). Chorioretinal hypoautofluorecent pot ≥ 125 micron uually, but not alway, had the clinically evident correlate of a punched-out car viible by color fundu photography. Chorioretinal hypoautofluorecent pot le than 125 micron, which could number in the hundred, typically were not viible by color fundu photography. All chorioretinal car viible by color fundu photography were viible by autofluorecence photography. During follow-up many patient developed new clinically evident chorioretinal car, which were preaged in earlier autofluorecence photograph. CNV had a hyperautofluorecent boundary, making it readily viible. Concluion Patient with MCP have much more widepread involvement of the RPE than would be upected by other mean of imaging. Autofluorecence photography upplie information about inflammatory damage and econdary CNV in a noninvaive manner.