Repective Role of Acquired and Congenital Infection in Preumed Ocular Toxoplamoi Original Reearch Article

Purpoe To analyze the role of acquired or congenital infection in cae of ocular toxoplamoi, and to compare their clinical manifetation. Deign Retropective, obervational cae erie. Method We analyzed the chart of conecutive patient with a diagnoi of ocular toxoplamoi. Data from the French program for the prevention of congenital toxoplamoi were ued to ae the origin of infection. The data included patientʹ erologic tatu prior to their ocular manifetation and patientʹ motherʹ erologic tatu before, during, and/or after pregnancy. Infection were categorized a congenital, acquired, or unknown. Reult Of 425 cae of ocular toxoplamoi, 100 (23.5%) were acquired, 62 (14.6%) were congenital, and 263 (61.9%) were of unknown origin. At the time of the tudy, the mean age of the patient with congenital ocular toxoplamoi wa 9.1 ± 8.8 year, and wa 21.7 ± 12.6 year in the patient with acquired ocular toxoplamoi (P < .0001). Bilateral chorioretiniti wa oberved in 4% of acquired cae and in 43.5% of congenital cae (P < .0001). In acquired infection, mean decimal viual acuity (VA) wa 1.0 (logarithm of the minimum angle of reolution [logMAR] 0.0 ± 1 line) in the bet eye and 0.4 (logMAR 0.4 ± 5 line) in the wort eye. In congenital cae, mean decimal VA wa 0.8 (logMAR 0.1 ± 4 line) in the bet eye and 0.25 (logMAR 0.6 ± 7 line) in the wort eye (P < .05). Concluion In cae where the origin of the infection could be determined, acquired infection were a more frequent caue of ocular toxoplamoi than congenital infection. Cae of congenital ocular toxoplamoi were more evere than acquired cae.