Author/Authors :
S. Vassal، نويسنده , , R. Taamma، نويسنده , , N. Marty، نويسنده , , A. Sardet، نويسنده , , P. d’Athis، نويسنده , , F. Brémont، نويسنده , , M.L. Dalphin، نويسنده , , P. Plésiat، نويسنده , , G. Rault، نويسنده , , J. Thubert، نويسنده , , S. Dominique، نويسنده , , J.F. Lemeland، نويسنده , , J. Derelle، نويسنده , , M.F. Blech، نويسنده , , M. Roussey، نويسنده , , M. Perrin، نويسنده , , A. Sautegeau، نويسنده ,
Abstract :
Background: To evaluate the contamination of delivery systems after an aerosol therapy session in patients with cystic fibrosis who have chronic Pseudomonas aeruginosa infection. Methods: Fifty-three patients with cystic fibrosis were enrolled in the study from March 1996 to June 1997. All patients were age 7 years or older and had P aeruginosa infection. They also had been treated with recombinant desoxyribonuclease and were capable of producing sputum for culture. Results: Nine devices were excluded for the study. A total of 44 nebulizers were included: 37 from patients with P aeruginosa colonization with a count of 106 colony-forming units/mL or more and 7 with a count of between 105 colony-forming units/mL and 106 colony-forming units/mL. Conclusion: This study demonstrates that in the absence of cleaning, nebulizers of patients with cystic fibrosis who are infected with P aeruginosa are likely to be contaminated by a pathogenic flora.
