Treatment of vaginal outflow tract obstruction in graft-versus-host reaction

We describe five patients with vaginal stenosis that was due to chronic graft-versus-host reaction after bone marrow transplantation. All patients underwent surgical procedures followed by local corticosteroids administration. Vaginal function was restored in all cases. This satisfactory result persists in the long term. (Am J Obstet Gynecol 2003;188:943-4.)