Title of article :
A cost-effectiveness analysis of management strategies for cervical intraepithelial neoplasia grades 2 and 3
Author/Authors :
Marc J. Kleinberg، نويسنده , , J.Michael Straughn Jr، نويسنده , , Jeffery S.A. Stringer، نويسنده , , Edward E. Partridge، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Pages :
3
From page :
1186
To page :
1188
Abstract :
Objective: This study was performed to compare the cost-effectiveness of strategies for the management of cervical intraepithelial neoplasia, grades 2 and 3 (CIN 2 and CIN 3). Study Design: A decision analysis compared six management strategies. The model was applied to hypothetic cohorts of 100,000 patients with CIN 2 and CIN 3. Results: In both analyses, cryotherapy (CRYO) was the least expensive and least effective strategy; total vaginal hysterectomy was the most expensive and most effective strategy. For CIN 2, loop electrosurgical excision procedure (LEEP) was more effective than CRYO but at a cost of $31,437 per additional cure and $1.8 million per additional cancer prevented. For CIN 3, LEEP was more effective than CRYO, but at a cost of $17,592 per additional cure and $1.0 million per additional cancer prevented. Conclusion: CRYO is a cost-effective strategy that is appropriate in resource-poor settings. LEEP is also cost-effective, but the improved efficacy compared with CRYO comes at a significant cost. Total vaginal hysterectomy is very effective but is economically unsound because of excessively high costs. (Am J Obstet Gynecol 2003;188:1186-8.)
Keywords :
Cervical dysplasia , Cost-effectiveness analysis
Journal title :
American Journal of Obstetrics and Gynecology
Serial Year :
2003
Journal title :
American Journal of Obstetrics and Gynecology
Record number :
642412
Link To Document :
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