Endometrial cancer in polyps associated with tamoxifen use,

We report 5 cases of carcinoma arising within tamoxifen-associated endometrial polyps. In 4 of 5 cases there were no other changes within the endometrium. Given these findings, the sonohysterographic differentiation between a polypoid structure and thickened endometrium does not eliminate the need for histologic sampling of the uterine cavity. (Am J Obstet Gynecol 1999;180:340-1.)