Title of article
Objective The purpose of this study was to determine the morbidity that is associated with curettage for the management of abortions in women who were infected with human immunodeficiency virus compared with women who were not infected with human immunode
Author/Authors
Beth A. Plunkett، نويسنده , , William A. Grobman، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
6
From page
998
To page
1003
Abstract
Objective
This study was undertaken to determine whether elective cesarean delivery to avert perinatal hepatitis C virus (HCV) transmission is cost-effective.
Study design
Using decision analysis, we compared 2 approaches: (1) offering elective cesarean delivery to avert perinatal HCV transmission, (2) performing a cesarean delivery only for obstetric indications. Lifetime cost and quality-adjusted-life-years (QALYs) for HCV-infected neonates were evaluated with Markov analysis. We assumed elective cesarean delivery reduces perinatal HCV transmission, and we varied both the risk reduction caused by elective cesarean delivery and the background risk of perinatal HCV infection.
Results
When elective cesarean section prevents all perinatal HCV transmission, 18 elective cesarean deliveries are necessary to avert 1 neonatal infection with a cost-effectiveness ratio of $34,812/QALY. At a background perinatal transmission rate of 7.7% elective cesarean deliveries is cost-effective only if it reduces the risk of perinatal transmission by more than 77%.
Conclusion
Elective cesarean delivery is cost-effective only if it substantially reduces the risk of perinatal HCV transmission.
Keywords
Cost-effectiveHepatitis CPerinatal transmission
Journal title
American Journal of Obstetrics and Gynecology
Serial Year
2004
Journal title
American Journal of Obstetrics and Gynecology
Record number
644308
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