Author/Authors :
Baradaran-Ghahfarokhi، Milad نويسنده Medical Radiation Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran &lMedical Physics and Medical Engineering Department , , Bagheri، Mohammad Hadi نويسنده Medical Imaging Research Center and Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran , , Faghihi، Reza نويسنده Medical Radiation Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran , , Hadad، Kamal نويسنده Medical Radiation Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran , , Sina، Sedigheh نويسنده Medical Radiation Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran , , Lotfi، Mehrzad نويسنده Medical Imaging Research Center and Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran , , Mosleh-Shirazi، Mohammad Amin نويسنده ,
Abstract :
Background: Safe dose escalation is highly desirable in radiotherapy for prostate
cancer. Prostate displacement due to bladder filling can be significant, so improved
targeting of the prostate by ultrasound imaging potentially allows for a reduction in the
target margin and consequently less toxicity. This study estimates the accuracy of
ultrasound for prostate and bladder volume measurements by comparing ultrasound
images taken immediately before and after magnetic resonance imaging to reduce the
effect of organ filling on measurement accuracy.
Methods: Three patients with a wide range of prostate sizes underwent pelvic
magnetic resonance imaging and ultrasound imaging. We tested the correlation between
the two measurements and the differences between the ultrasound measurements
before and after magnetic resonance imaging using statistical analysis.
Results: Based on a total number of 18 volume measurements, a strong linear
correlation was found (r=0.95), but there were no significant differences between
ultrasound imaging performed before and after magnetic resonance imaging (P=0.809).
Conclusion: Our results provide additional evidence that ultrasound imaging
measures bladder and prostate volumes in a reproducible and accurate manner over a
wide range of volumes, which enables its use with different fractions of prostate
radiotherapy.
