Author/Authors :
Zaky، Amen Hamdy نويسنده Departments of Medical Oncology, Radiotherapy and Surgical Oncology, South Egypt Cancer Institute, Assuit University, Assuit, Egypt , , Abd El-Wanis، Mostafa Elsayed نويسنده Departments of Medical Oncology, Radiotherapy and Surgical Oncology, South Egypt Cancer Institute, Assuit University, Assuit, Egypt , , Hamza، Hisham نويسنده Departments of Medical Oncology, Radiotherapy and Surgical Oncology, South Egypt Cancer Institute, Assuit University, Assuit, Egypt , , Abdel-Hafez، Hisham Zayan نويسنده Dermatology Department, Faculty of Medicine, Assuit University , , Abdel-Azim، Nagwa Essa نويسنده Dermatology Department, Faculty of Medicine, Assuit University ,
Abstract :
Background: Cutaneous metastasis is defined as the spread of malignant cells from
a primary malignancy to the skin. Generally, cutaneous involvement from internal
malignancies is uncommon. No reports have focused on the cutaneous metastasis profiles
in Egypt or the Middle Eastern population. In this study, we seek to determine the rates
at which different internal malignancies give rise to cutaneous metastases upon first
diagnosis of the primary tumor.
Methods: Patients with internal malignancies who attended the South Egypt
Cancer Institute from January 2004 through May 2010 were examined and followed
to identify cutaneous metastases, which were confirmed by biopsy and histological
evaluation.
Results: Among 2208 cases of internal malignancies, 48 cases of cutaneous
metastases were detected. The clinical profiles were similar to those from western and
Asian countries, although the frequencies of primary tumors differed. Most commonly
in Egypt breast cancer and urinary bladder cancers were seen.
Conclusion: The risk of skin metastases depends largely on the characteristics of
tumor cells, which are similar among different groups.
