Methods for Isolation of Bone Marrow Stem Cells: Comparative Analysis

During the past decade, regenerative medicine has emerged as a key technology in the next generation of medical care, and cell therapy and organ repair using stem cells have become very attractive options for regenerative medicine. The application of stem cells in regenerative medicine has required modified methods for isolation. Furthermore, the proc- ess of cell separation plays an important role in cell therapy and regenerative medicine using stem cells. So, in this review, we compare different methods for the separation of cells from bone marrow for transplantation to humans, with emphasis on the advantages and disadvantages of each method.