SIMULTANEOUS DEVELOPMENT OF KAPOSIʹS SARCOMA AND LYMPHOMA IN A RENAL TRANSPLANT RECIPIENT

Kaposi’s sarcoma (KS) and non-Hodgkin’s lymphoma have been described following renal transplantation as separate entities. We report simultaneous development of KS and lymphoma in a 45-year-old female after renal transplantation. Following transplantation, the patient received immunosuppressive treatment with cyclosporine, azathioprine and prednisolone, and maintained normal serum creatinine. Four and a half months after transplantation, she developed KS skin lesions and cervical lymphadenopathy. A cervical lymph node biopsy revealed both KS and lymphoma. Immunosuppression was discontinued 2 weeks later, and she responded with complete regression of both tumors within about 2 months. The patient was followed up for 32 months with no tumor recurrence and the allograft function has been stable with prednisolone therapy. It is important to keep in mind that, after kidney transplantation, one or more malignancies can develop either as separate entitles or simultaneously, and reduction in the immunosuppression regimen may lead to complete remission.