• Title of article

    Facile Entries for Regioselective Synthesis of [1,2,4]Triazolo-[4,3-a]pyrimidin-5(1H)-ones from 2-Thiouracil

  • Author/Authors

    A.S. Shawalia، نويسنده , , I.M. Abbasa and A.M. Mahranb، نويسنده ,

  • Issue Information
    فصلنامه با شماره پیاپی سال 2004
  • Pages
    7
  • From page
    33
  • To page
    39
  • Abstract
    Three new alternative synthetic strategies based on reactions of hydrazonoyl halides 3 with 2-methylthiouracil 2 and treatment of either 2-pyrimidinyl thiohydrazonates 8 or the diazonium coupling products of active (pyrimidin-2- ylthio)methylene compounds 12 with sodium ethoxide in ethanol are described for the title compounds. The mechanisms and regiochemistry of the studied reactions are discussed
  • Keywords
    synthetic methods , Rearrangement , hydrazones , 2 , Heterocycles , 4-Triazolo-pyrimidine , 1
  • Journal title
    Journal of the Iranian Chemical Society (JICS)
  • Serial Year
    2004
  • Journal title
    Journal of the Iranian Chemical Society (JICS)
  • Record number

    666428