An Efficient Synthesis of New Chiral Oxazolines

Several new chiral oxazolines were prepared conveniently in good to high yields using a two-step synthesis involving formation of an optically active amide, in situ conversion of the amide into tosylate (OTs) and finally ring closing reaction under MW irradiation (800 W) in solvent free condition. A comparison of these results with those obtained from the ring closing reaction under classical conditions was also made.