Nebular abundances in galaxies: Beware of biases

The derivation of nebular abundances in galaxies using strong line methods is simple and quick. Various indices have been designed and calibrated for this purpose, and they are widely used. However, abundances derived with such methods may be significantly biased, if the objects under study have different structural properties (hardness of the ionizing radiation field, morphology of the nebulae) than those used to calibrate the methods. Special caution is required when comparing the metallicities of different samples, like, for example, blue compact galaxies and other emission line dwarf galaxies, or samples at different redshifts.