Rhodium/diene-catalyzed asymmetric 1,4-addition of arylboronic acids to (alpha),(beta)-unsaturated Weinreb amides

Rhodium/chiral diene (S,S)-3b complex has been found to effectively catalyze the 1,4-addition of arylboronic acids to (alpha),(beta)-unsaturated Weinreb amides, furnishing useful (beta)-chiral Weinreb amides in high enantioselectivity.