Title of article
Finding Exact and Solo LTR-Retrotransposons in Biological Sequences Using SVM
Author/Authors
Torabi Dashti، Hesam نويسنده Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics and Center of Excellence in Biomathematics, Universit , , Masoudi-Nejad، Ali نويسنده Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics and Center of Excellence in Biomathematics, Universit , , Zare، Fatemeh نويسنده Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics and Center of Excellence in Biomathematics, Universit ,
Issue Information
فصلنامه با شماره پیاپی 62 سال 2012
Pages
6
From page
111
To page
116
Abstract
Finding repetitive subsequences in genome is a challengeable problem in bioinformatics research area. A lot of approaches have been proposed to solve the problem, which could be divided to library base and de novo methods. The library base methods use predetermined repetitive genome’s subsequences, where library-less methods attempt to discover repetitive subsequences by analytical approaches. In this article we propose novel de novo methodology which stands on theory of pattern recognition’s science. Our methodology by using Support Vector Machine (SVM) classification and clustering methods could extract exact and Solo
LTR-retrotransposons. This methodology issued to show complexity efficiency and applicability
of the pattern recognition theories in bioinformatics and biomathematics research areas.
We demonstrate applicability of our methodology by comparing its results with other well-known
de novo method. Both applications return classes of discovered repetitive subsequences, were their results when had applied on show more that 90 percents similarities.
Journal title
Iranian Journal of Chemistry and Chemical Engineering (IJCCE)
Serial Year
2012
Journal title
Iranian Journal of Chemistry and Chemical Engineering (IJCCE)
Record number
682541
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