Title of article :
Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
Author/Authors :
Baghaban Eslaminejad، Mohamadreza نويسنده , , Jahangir، Shahrbanoo نويسنده Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for StemCell Biology and Technology, ACECR, Tehran, ,
Issue Information :
فصلنامه با شماره پیاپی 23 سال 2012
Abstract :
Advances in stem cell biotechnology hold great promise in the field of tissue engineering and
regenerative medicine. Of interest are marrow mesenchymal stem cells (MSCs), embryonic stem
cells (ESCs), and induced pluripotent stem cells (iPSCs). In addition, amniotic fluid stem cells (AFSCs)
have attracted attention as a viable choice following the search for an alternative stem cell
source. Investigators are interested in these cells because they come from the amniotic fluid that is
routinely discarded after birth. There have been multiple investigations conducted worldwide in an
attempt to better understand AF-SCs in terms of their potential use in regenerative medicine. In this
review we give a brief introduction of amniotic fluid followed by a description of the cells present
within this fluid. Their history related to stem cell discovery in the amniotic fluid as well as the
main characteristics of AF-SCs are discussed. Finally, we elaborate on the potential for these cells
to promote regeneration of various tissue defects, including fetal tissue, the nervous system, heart,
lungs, kidneys, bones, and cartilage.
Journal title :
International Journal of Fertility and Sterility
Journal title :
International Journal of Fertility and Sterility